ARTIFICIAL INSEMINATION WITH DONOR SPERM

  

                        INSEMINATION WITH DONOR SPERM

     Sperm donation is a valid alternative in cases where the man has no sperm in the ejaculate or has significant sperm abnormalities, suffers from a genetic disease that does not want to transmit to their offspring, it is a sero-discordant couples for HIV or is 0 positive man and woman is negative and 0 have severe Rh sensitization.

in recent years has increased the use of donor sperm in women 'alone' or partner with other women.

The donor sperm can be used for artificial insemination (intracervical or intrauterine) or in vitro fertilization (IVF-ICSI).

Inseminations can be performed in a spontaneous cycle (using some method to synchronize with ovulation) or ovulatory cycle stimulation with drugs that promote fertility. This decision will depend on the presence or absence of normal ovulation and age and gynecological / reproductive women characteristics.

The success rates of inseminations of this type are around 15% per attempt, so it may be necessary to perform several inseminations to achieve pregnancy. Given this success rate, we would expect that most patients become pregnant within the first 9 months. The most important reasons for failure among patients participating in a program of insemination with donor sperm include abandonment and abnormalities of fertility thereof.

Artificial insemination with donor sperm is an assisted reproductive technology (ART) which is indicated in: 

     Couples who have a serious or irreversible sperm disorder.

Couples in which the husband presents a risk of spreading disease to their offspring.

Women without male partner who desire pregnancy.

The selection of sperm donors is the responsibility of sperm banks. Before being accepted donors are subjected to a rigorous examination in order to avoid the possible transmission of enfernedades to offspring. This test also includes the study of semen (semen), a genetic study (karyotype) and a study of infectious diseases (hepatitis, syphilis, AIDS ...).

Generally they performed up to six cycles of insemination. When a cycle is not successful it is important to review it and make the necessary changes (change the dose, stricter controls ...). If you still no pregnancy is achieved should consider the possible existence of other anomalies and / or the desirability of using other assisted reproduction techniques. (TRA).

In some cases it is advisable to use a stimulatory treatment with oral tablets ovulation or subcutaneous (ovulation induction) in order to ensure that ovulation occurs correctly. These treatments, although they may produce some complications, intended to ensure that ovulation occurs correctly in order to increase the chances of getting pregnant.

sted reproduction   >   donation and assisted reproduction   >   Donation Semen

Donor Selection

     First, any man who wishes to become a sperm donor has to be clear that this is a voluntary, anonymous and altruistic act consisting of the delivery of their sperm, where his genetic material, so they can be used later in treatments of assisted reproduction with intent to achieve a pregnancy and thus the birth of a baby.

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The selection of sperm donors follow a very strict criteria established by law. In fact, only one in 15 young people who undergo screening tests finally gets to be a donor.

Selection criteria for sperm donation

     For a guy can act as a sperm donor, you must meet a number of criteria regulated by law discussed below.

Age: between 18 and 45 years.

No family or personal chronic or serious illness that can affect offspring and no history of birth defects in your family history. So it can not be adopted because their history not known.

Anonymity and altruism donors are financially compensated for their activity, that is, you are given a symbolic amount of money for the inconvenience of the process, missing work or travel.

Absence of hereditary diseases.

Absence of infectious diseases.

adequate physical and psychological health.

Absence of risk practices.

negative serology HIV, hepatitis B and C, syphilis, etc.

Absence of sexual diseases as diseases like chlamydia and gonococcus.

Suitable values discussed in seminal seminogram both before and after freezing.

Dismiss liver disease.

Serology at 6 months by the HIV window period.

normal karyotype.

Medical tests on the donor

     In addition to interviews with professionals and a psychological study, the donor has to undergo various medical tests to ensure that it meets the requirements for donation.

One of the most important tests that the donor undergoes is the study or analysis of important seminal values for fertilization by a full semen analysis .

To be accepted as a donor, it is necessary seminogram unveil an excellent semen quality, with adequate mobility, morphology and sperm concentration . In addition, it freezes and thaws a small part of the sample to check the survivability before freezing, which is essential. It is what is known as evidence of thawing .

Moreover, the following tests are performed:

Microbiological culture of the sample to rule out genital infections.

Blood count and biochemical blood count to rule out liver disease.

detailed physical examination.

Blood tests to rule out infections, serious illnesses and determine the blood type and Rh factor.

a study of chromosomes (karyotype) is also made in order to determine whether there are chromosomal abnormalities such as deletions or translocations.

     If the donor exceeds these medical tests, both the CBC and serology are repeated after 6 months from acceptance and start in the sample reservoir, to check the values ​​and safely discard the presence of HIV (period of this virus window is 6 months).

Award the donor to a patient

Since the donation is anonymous, when a woman or a couple need donor sperm is clinical or reproductive center which makes the award of semen donor taking into account the compatibility of blood group and phenotypic characteristics such as race, weight , height, hair color and eye.

If a woman or partner is pregnant with semen from a particular donor, it is possible to book semen doses of the same donor for use in a reproduction treatment in the future when a second child desired.